What is levothyroxine?
Levothyroxine was invented in 1927 and is often called L-thyroxine. It is included in the list of essential medicines of the World Health Organization. This is a manufactured form of the hormone thyroid, a synthetic T4 thyroid replacement hormone, which is used for the treatment of the thyroid hormone deficiency, even in severe cases such as the so called myxedema coma. Levothyroxine is also applied in case of thyroid tumors. The drug is not indicated for weight loss.
The levothyroxine drug can be taken by mouth or can be given as an injection. The maximum effect from the specific dose could take up to one month and a half in order to occur. Some of the side effects that could occur as well include anxiety and sweating, weight loss and sleep troubles, and tremors. The drug can also cause fast heart rate and is thus not recommended to people who suffered from a recent heart attack. Naturally, the dosage should always be based on regular measurements of the T4 levels and TSH in the blood.
Levothyroxine is a generic medication and in recent years was one of the most commonly prescribed medication in the United States of America. It is very effective in treating hypothyroidism or the condition of the underactive thyroid.
Since the thyroid produces the T3 and T4 hormones that control metabolism and the rate at which the body burns oxygen and calories, hypothyroidism can result in weight gain. By taking levothyroxine, one can replace the missing hormones and boost the metabolism, which may result in weight loss. When the correct balance of the thyroid hormone is reached, the metabolism is as it should be and losing weight is possible and easy.
What is levothyroxine used for?
Usually used to treat hypothyroidism, Levothyroxine is also a choice by people who need lifelong thyroid hormone therapy. The prescribed doses of that drug can normalize the TSH, but this does not mean that they can normalize the cholesterol.
The absorption of the orally taken levothyroxine is done 40-80% by the gastrointestinal tract, and the majority of the drug is absorbed from the upper ileum and jejunum. The absorption is increased by fasting and is decreased in case of malabsorption syndromes, certain foods, and also with age.
Almost all circulating thyroid hormones are connected to the plasma proteins and only the free hormone is active metabolically. The half-life elimination of the thyroid hormones is up to 4 days for people with hyperthyroidism, up to one week for people that show normal lab results and up to 10 days for people that have hypothyroidism. Approximately 80% of the thyroid hormones are eliminated by the kidneys and the urinary excretion. The other 20 % of the T4 are eliminated in the stool.
It should be pointed out that Levothyroxine is contraindicated for those people who have hypersensitivity to levothyroxine sodium or any of its components, people who suffer from acute myocardial infarction, and people that have thyrotoxicosis, and uncorrected adrenal insufficiency.
What else is levothyroxine used for? During recent years some bodybuilders take T3 (triiodothyronine) to lose weight. T3 is potent and absorbed easier, and can raise/lower thyroid plasma levels quicker as it has a shorter half-life. The Thyroid hormones (T3/T4) increase the metabolism, and along with that they increase the body temperature, and the heart rate. In this way more calories are burned and more weight is loss. It is very important to note that the thyroid hormones are catabolic in nature and should not be used as the sole approach to weight loss.
The thyroid medication is often used by bodybuilders who plan to attend a contest. T4 is usually used when T3 cannot be found. We do offer and sell the drug and it comes under the name ‘L-Thyroxine’. There is a serious interest in the drug, especially after an article by Dr. James Daemon was published. Levothyroxine spares the muscles and results in synergy with growth hormone. Typically, bodybuilders use it when dieting and on cutting cycles which include Growth hormone. It is believed that T4 is not that harsh on the muscle tissue and bodybuilders can maintain more muscle when on a diet by using T4, compared to when they use T3.
Levothyroxine weight loss
The metabolism works like that – when it is slow you burn fewer calories and if you continue to eat the same amount of food, you start to gain weight. It should be noted that the more serious the hypothyroidism is, the greater the weight gain is. When the hypothyroidism is under control by taking Levothyroxine, the result is weight loss, which is not greater than 10 percent of the current body weight.
By taking Levothyroxine for several weeks, the metabolism is back to normal and the hypothyroidism is corrected. Then one can gain or lose weight as a normal human being with no thyroid issues. The usage of higher dose of L-thyroxine in order to speed the weight loss is not recommended as it can result in side effects such as heart attack, loss of bone mass and osteoporosis, angina and irregular heartbeat.
The abuse of the prescribed medication can lead to an overactive thyroid and condition of hyperthyroidism. The drug can take 2 to 4 weeks for the symptoms to fade away. Always buy ‘L-Thyroxine’ from reliable sources.
Levothyroxine side effects
The side effects of the Levothyroxine are associated and caused by incorrect dosages. If the TSH valves get long-term suppression below the normal values, this can cause decrease in the bone mineral density and cardiac side-effects. The higher dosage of Levothyroxine can cause hyperthyroidism. The overdose can bring insomnia and confusion, nausea and abdominal pain, weight loss or increased appetite. Some users can show allergic reactions to the drug, such as shortness of breath, difficult breathing, face and tongue swelling.
The acute overdose can result in fever and coma, heart failure and adrenal insufficiency, while the mass overdose can be life-threatening. The over dosage effects can appear 6 hours to 10-11 days after ingestion. If you ‘L-Thyroxine’ from reliable sources and use it properly, no side effects should be expected.
Levothyroxine interaction with other substances
Some substances and foods can interfere with the thyroxine absorption such as magnesium and aluminum. The coffee may interfere with the absorption of Levothyroxine and the grapefruit juice can delay the absorption. Soy, Iron and calcium supplements also interfere with the body absorption of oral levothyroxine. The toxicity of the drug is increased if taken along with ketamine, antidepressants, lithium.
When to take levothyroxine?
Usually the Levothyroxine users are instructed to take the drug one hour before breakfast on an empty stomach and with water only, but dairy products after that should be avoided. According to various researches, the TT4 concentration levels get significantly lower when Levothyroxine is taken along with milk as the calcium in the milk interfere with the full absorption of levothyroxine.
As an alternative, the drug can be taken at night when no other medications are taken and when there are least four hours between the last meal and the taking of Levothyroxine.
We sell Levothyroxine under the name ‘L-Thyroxine’ and you can order it now.